TCTR20210802001已完成4 期
Effect of transcranial direct current stimulation at the left dorsolateral prefrontal cortex (DLPFC) combined with quadriceps strengthening exercise in chronic knee osteoarthritis: A double blinded, randomised sham-controlled trial
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 32
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 50 Years 至 90 Years（—）
- 性别
- All
入选标准
- •1. Age 50 - 90 years old
- •2.Diagnosed chronic knee osteoarthritis by American College of Rheumatology present with knee joint pain plus at least 3 of following
- •2.1Age more than 50 yr
- •2.2Morning stiffness more than 30 mins
- •2.3Crepitus
- •2.4Bony enlargement
- •2.5Bony tenderness
- •2.6No palpable warmth
- •3.Clinical knee pain by VAS 40-70 mm
- •4.Kellgren and Lawrence classification system grading 1 - 3
- •5.Knee pain at least 3 mo.
- •6.Can sit with support more than 20 mins
- •7.Not participate in others trial
- •8.Willing to participate by themselves
排除标准
- •1.Hemodynamic or Neurological condition not stable
- •2.Cannot communicate or follow command
- •3.Acute inflammation on studied side
- •4.Knee joint replacement on studied side
- •5.History of intraarticular injection at studied side: steroid within 3 months and hyaluronic acid within 6 month
- •6.Have to had pain killer such as NSIADs within 2 weeks
- •7.History of MDD
- •8.History of non-invasive brain stimulation such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS)
- •9.Contraindications to tDCS
- •9.1Skin pathology, infection, wound, vasculitis at stimulate site
- •9.2History of bleeding tendency
- •9.3History of seizure or in family
- •9.4History of migraine
- •9.5History of brain surgery
- •9.6History of traumatic brain injury which alteration of conscious more than 15 min
- •9.7Neurodeficit
- •9.8Implanted metal device: pacemaker, metal plate, wires
- •9.9Pregnancy
- •9.10History adverse effect from other brain stimulation
研究者
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