TCTR20210802001
Completed
Phase 4
Effect of transcranial direct current stimulation at the left dorsolateral prefrontal cortex (DLPFC) combined with quadriceps strengthening exercise in chronic knee osteoarthritis: A double blinded, randomised sham-controlled trial
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Faculty of Medicine, Chulalongkorn University
- Enrollment
- 32
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Age 50 \- 90 years old
- •2\.Diagnosed chronic knee osteoarthritis by American College of Rheumatology present with knee joint pain plus at least 3 of following
- •2\.1Age more than 50 yr
- •2\.2Morning stiffness more than 30 mins
- •2\.3Crepitus
- •2\.4Bony enlargement
- •2\.5Bony tenderness
- •2\.6No palpable warmth
- •3\.Clinical knee pain by VAS 40\-70 mm
- •4\.Kellgren and Lawrence classification system grading 1 \- 3
Exclusion Criteria
- •1\.Hemodynamic or Neurological condition not stable
- •2\.Cannot communicate or follow command
- •3\.Acute inflammation on studied side
- •4\.Knee joint replacement on studied side
- •5\.History of intraarticular injection at studied side: steroid within 3 months and hyaluronic acid within 6 month
- •6\.Have to had pain killer such as NSIADs within 2 weeks
- •7\.History of MDD
- •8\.History of non\-invasive brain stimulation such as transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS)
- •9\.Contraindications to tDCS
- •9\.1Skin pathology, infection, wound, vasculitis at stimulate site
Outcomes
Primary Outcomes
Not specified
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