The effect of stereotactic radiotherapy on cognitive functioning and quality of life of patients with one to three brain metastases: a prospective study
Recruiting
- Conditions
- Brain metastasessecondary brain tumours1002747610029211
- Registration Number
- NL-OMON32515
- Lead Sponsor
- Medisch Centrum Haaglanden
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
1. Patient with * 3 newly diagnosed brain metastases,
2. Adult (* 18 years),
3. Patient will be treated with SRT,
4. Written informed consent.
Exclusion Criteria
1. Patient has had any treatment (i.e. surgery, biopsy, WBRT and/or SRT) for his brain metastatic disease,
2. Patient will be treated with both WBRT and a SRT boost,
3. Patient has insufficient mastery of the Dutch language,
4. patient has other neurological or psychiatric conditions which could interfere with the results,
5. according to the treating physician, patient is (expected to be) unable to participate in the follow up period, because of serious physical or mental conditions (i.e. a KPS score below 70),
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Indicators of cognitive functioning, fatigue, quality of life and radiological<br /><br>features will be assessed as primary outcomes at baseline (before SRT), one<br /><br>month after completion of SRT, and again three months and six months after<br /><br>completion of SRT.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Neurological functioning and self care (in daily life)</p><br>