A clinical trial to find out the effect of Atorvastatin on dilatation of forearm blood vessel,in patients with Systemic Sclerosis.
Not Applicable
- Conditions
- Health Condition 1: M349- Systemic sclerosis, unspecified
- Registration Number
- CTRI/2020/07/026894
- Lead Sponsor
- Intra Mural Research Fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients with Systemic Sclerosis with a duration of less than 3 years from the first non-Raynauds symptom, classified as per ACR-EULAR 2013 classification criteria
2.Between 18-65 years of age.
3.No use of lipid-lowering medication within last 6 months.
Exclusion Criteria
1.Pregnancy
2.Renal dysfunction
3.Diabetes mellitus
4.Known cardiovascular disease or a prior history of stroke
5.History of liver disease
6.New or changed dose of calcium channel blockers or angiotensin receptor blocker in the last 4 weeks
7.known allergy or adverse reaction to statins.
8.Smoking
9.Overlap syndromes.
10.Patients with digital gangrene despite being on Calcium Channel Blockers and/or Phosphodiesterase inhibitors.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method