Longitudinal Study of the Pulmonary Function Testing of Pregnant Women Exposed to Air Pollution in São Paulo

University of Sao Paulo General Hospital0 sites120 target enrollmentAugust 2011

ConditionsLung Diseases

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Lung Diseases
Sponsor: University of Sao Paulo General Hospital
Enrollment: 120
Primary Endpoint: Effect of air pollution in the spirometry of 120 pregnants, evaluated by individual passive samplers in the first (T1) and third (T3) trimesters of pregnancy, using the non-parametric analysis for repeated measures
Status: Completed
Last Updated: 9 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

A single group of pregnant women who was analyzed in the first and in the third trimesters of pregnancy

Detailed Description

A single group of 120 pregnant women separated in smokers (n = 17) and nonsmokers (n = 103) and first pregnancy (n = 54) or multiparous (n = 66) who underwent pulmonary function test and used the individual passive sampler in the first and third trimesters of pregnancy

Registry

clinicaltrials.gov

Start Date

August 2011

End Date

November 2014

Last Updated

9 years ago

Study Type

Interventional

Study Design

Single Group

Sex

Female

Investigators

Sponsor

University of Sao Paulo General Hospital

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•prior informed consent;
•single pregnancy;
•topical and feasible;
•gestational age of less than 13.86 weeks at the first evaluation;
•absence of preexisting maternal diseases

Exclusion Criteria

•withdrawal from the project;
•abortion;
•inadequate pulmonary function test

Outcomes

Primary Outcomes

Effect of air pollution in the spirometry of 120 pregnants, evaluated by individual passive samplers in the first (T1) and third (T3) trimesters of pregnancy, using the non-parametric analysis for repeated measures

Time Frame: Through study completion, an average of 3 year

Secondary Outcomes

Evaluation of the influence of smoking and parity and the results of spirometry of all pregnants exposed to pollution comparing the frequency of events held by Wilcoxon and the Mann Witney test(Through study completion, an average of 3 year)