跳至主要内容
临床试验/CTRI/2019/08/020830
CTRI/2019/08/020830尚未招募不适用

A Comparative Clinical Study to Evaluate the Efficacy of Katutumbi taila and Himsradi taila as Marsha Nasya in Hypothyroidism

Dr Aishwarya Lakshmi BR1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2019年8月30日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
1.Serum TSH

研究概览

简要总结

Nasya Karma, one among Panchakramais a process by which medicated oil isadministered through the nostrils to alleviate diseases of jatrurdwa.

Thesedentary lifestyle and stress filled modern era has led to alterations in theactivities of neuro-endocrine systems causing newer health challenges likehypothyroidism. Hypothyroidism,occurs when the thyroid gland does not produce enough thyroid hormones. It iscontinued to be posing a major health challenge in both developing anddeveloped world. There is 4.5% prevalence of Hypothyroidism in developed world.The prevalence of subclinical hypothyroidism in developed world is 4-15%. Theprevalence of hypothyroidism in urban India is 10.95%. Major portion ofHypothyroidism remain undetected. Incidence of Hypothyroidism is more infemales (7:1) and elderly people1. Managementof Hypothyroidism with the modern drugs may bring the value of TSH and T4 tonormal range, but increased dosage and continuous medication make the patientdrug dependent till the end of mortal life. So a better and safer therapy isneeded for the patient society through the heritage of Ayurveda. Hence aneffort is made to treat hypothyroidism in a safer and effective way.

Thethyroid disorders can be studied under Galaganda.Involvement of Kapha is invariableassociated with Kupita vata and dusta Medas2a. The stana of thyroid gland being jatrurdwa and being a kapha stana, Marsha Nasya is selected for its shodana action.Previouslya work on Katutumbi taila Nasya with katu taila3a base was done,which had very good results. However Subjects had irritation in nose due to itsatiteekshna guna, hence in order toreduce its teekshnata, Katutumbi tailawith tila taila4a as thebase is used in present study. This is compared to Himsradi taila4b Nasya which also has usna and teekshna guna, thus the desiredshodana effect is achieved.

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
Open Label

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Subjects with clinical signs and symptoms of Hypothyroidism and Serum Thyroid Levels suggesting Hypothyroidism
  • Subjects fit for Marsha Nasya.

排除标准

  • Subjects diagnosed with cardiac disorders, Hashimoto thyroiditis, Thyrotoxicosis, congenital anamolies and carcinomas of the thyroid gland, Myxedema and its complications
  • Pregnant and Lactating women.

结局指标

主要结局

1.Serum TSH

时间窗: 45 days

3.Hairfall

时间窗: 45 days

2.Easy Fatigue

时间窗: 45 days

次要结局

  • 1.Dry Skin(2.Somnolence)

研究者

发起方
Dr Aishwarya Lakshmi BR
申办方类型
Other [self]

研究点 (1)

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