A study to compare efficacy and tolerability of Oral Azithromycin versus Oral Doxycycline with topical Clindamycin in subjects with moderate to severe Acne Vulgaris
- Conditions
- Health Condition 1: null- ACNE VULGARIS GRADE 2 AND GRADE 3Health Condition 2: L989- Disorder of the skin and subcutaneous tissue, unspecified
- Registration Number
- CTRI/2018/05/013916
- Lead Sponsor
- Dr Apoorva
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Willingness to give written informed consent and availability for regular followup.
Subjects with Acne Vulgaris of grade 2 and 3 as per the investigators global assessment scale.
Subjects must be willing to refrain from using all other topical Acne medications or antibiotics during the 8 week treatment period.
Subjects with severe acne, nodulocystic lesions, acne conglobate, acne fulminans, acne rosacea, secondary(drug induced) acne.ion ingestion.
Subjects with a history of hypersensitivity or allergy to any study medication ingredients.
Subjects who have participated in any investigational drug study within 30 days prior to baseline will be excluded from participation.
Female subjects who are pregnant,lactating or planning to become pregnant during study participation.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess and compare the efficacy and tolerability of oral Azithromycin and oral Doxycycline in subjects with grade 2 and 3 acne vulgarisTimepoint: 8 weeks
- Secondary Outcome Measures
Name Time Method Quality of life will be assessed using DLQI scoreTimepoint: 8 weeks