Comparison of IV Nalbuphine Versus Ibuprofen for Postoperative Pain Control in Cesarean Section
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Efficacy in pain control
研究概览
简要总结
The local data is insufficient to directly compare IV nalbuphine versus ibuprofen among people in this region. The findings of this study would add to the existing data and would be helpful for health providers to opt for a better option for postoperative pain relief following a cesarean section under general anesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Parturient females
- •Aged between 18-45 years
- •Gestational age above 32 weeks
- •ASA class I to II
- •Anticipated hospital stay for at least 24 hours
排除标准
- •Known allergy to the drugs being evaluated in this study
- •Renal and/or hepatic impairment (as per medical record)
- •History of bronchial asthma or history or risk of intracranial hemorrhage (as per medical record)
- •Low platelets count (<70000) or with bleeding diathesis
- •BMI above 30 kg/m2
研究组 & 干预措施
IV Ibuprofen Group
Females in this group (n=40) were given 800 mg Ibuprofen in 200 cc normal saline intravenously at the time of arrival in the ward
干预措施: Ibuprofen (Drug)
IV Nalbuphine
Patients in this group received 20 mg nalbuphine in 200 cc normal saline IV at the time of arrival in the ward.
干预措施: Nalbuphine (Drug)
结局指标
主要结局
Efficacy in pain control
时间窗: At 1 hour, 3 hours, and 6 hours.
Outcome was noted in the form of VAS pain scores. Scores from 1 to 3 were labeled as mild pain, 4 to 6 as moderate pain, and 7 to 10 as severe pain.
次要结局
未报告次要终点
研究者
Muhammad Aamir Latif
RESnTEC, Institute of Research
RESnTEC, Institute of Research