Comparison of IV Nalbuphine Versus Ibuprofen for Postoperative Pain Control in Cesarean Section
- Registration Number
- NCT06594224
- Lead Sponsor
- Muhammad Aamir Latif
- Brief Summary
The local data is insufficient to directly compare IV nalbuphine versus ibuprofen among people in this region. The findings of this study would add to the existing data and would be helpful for health providers to opt for a better option for postoperative pain relief following a cesarean section under general anesthesia.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 80
Inclusion Criteria
- Parturient females
- Aged between 18-45 years
- Gestational age above 32 weeks
- ASA class I to II
- Anticipated hospital stay for at least 24 hours
Exclusion Criteria
- Known allergy to the drugs being evaluated in this study
- Renal and/or hepatic impairment (as per medical record)
- History of bronchial asthma or history or risk of intracranial hemorrhage (as per medical record)
- Low platelets count (<70000) or with bleeding diathesis
- BMI above 30 kg/m2
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description IV Ibuprofen Group Ibuprofen Females in this group (n=40) were given 800 mg Ibuprofen in 200 cc normal saline intravenously at the time of arrival in the ward IV Nalbuphine Nalbuphine Patients in this group received 20 mg nalbuphine in 200 cc normal saline IV at the time of arrival in the ward.
- Primary Outcome Measures
Name Time Method Efficacy in pain control At 1 hour, 3 hours, and 6 hours. Outcome was noted in the form of VAS pain scores. Scores from 1 to 3 were labeled as mild pain, 4 to 6 as moderate pain, and 7 to 10 as severe pain.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Nishtar Hospital
🇵🇰Multan, Punjab, Pakistan
Nishtar Medical University
🇵🇰Multan, Punjab, Pakistan