"A Randomised Controlled Clinical Trial To Evaluate The Role Of Jyotishmati Taila In The Management Of Sidhma Kushta Vis-A-Vis Pityriasis Versicolor"
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- To reduce the itching
研究概览
简要总结
A RANDOMIZED CONTROLLED CLINICAL TRIALTO EVALUATE THE ROLE OF JYOTISHMATI TAILA IN THE MANAGEMENT OF SIDHMA KUSHTA VIS-À-VIS PITYRIASIS VERSICOLOR
J**yotishmatitaila is one of the classical preparation mentionedin Ashtanga Hridaya for Sidhmakushta. It contains alkaline water of Apamarga (Achyranthes aspera)and oil extracted seeds of Celastrus paniculatus. Various studies showsthat this oil is having antioxidant, antibacterial, antifungal andhypolipidemic properties and foundhighly significant in tissue epithlialization.The oilin combination with Apamarga Kshara is known to have Kapha haraaction and Sidhma nashaka. But the efficacy of the formulation is notdocumented. Hence effort has been made to evaluate the efficacy of topicalapplication of Jyotishmati Taila in the management of Sidhma kushta.
In this study 40 subjects, 20 in each group will be selected as per inclusion and exclusion criteria.
Group A (study group) - 20 subjects will be subjected to externalapplication of Jyotishmati taila over the affected part and retained forminimum 30 minutes Dose: Twice daily(Morning and Night) q.s to cover affected site Duration: 30 days.
Group B (control group) - 20 subjects will be subjected to externalapplication of Gandakadi lepa over the affected part and retained forminimum 30 minutes Dose: Twice daily(Morning and Night) q.s to cover affected site Duration: 30 days.
Treatmentperiod: 30 days (Clinical assessmentwill be done on 15thand 30th day of treatment)
Follow up Period: Will be on 45th & 60thday of the treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with classical signs and symptoms of Sidhma Kushta
- •Patients with positive KOH test for fungal dermatophytes
- •Patients belonging to either gender will be included
- •Persons willing to participate in the study.
排除标准
- •1.Pregnancy and lactation 2.Patients having P.versicolor with lacerated wounds and associated with secondary bacterial infections and major skin problems 3.Patients suffering from uncontrolled systemic disorders which worsen the conditions ( eg: DM, HIV etc ) 4.Patients presenting with hypopigmentary disorders of skin other than Pityriasis versicolor 5.Patches caused due to burns, chemical explosion etc.
- •6.Patients who are on topical & systemic antifungal therapy for the same problem.
结局指标
主要结局
To reduce the itching
时间窗: 7 days
次要结局
- To minimize the scaly flakes & patch size(30 days)