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Clinical Trials/CTRI/2025/09/094419
CTRI/2025/09/094419Not yet recruitingNot Applicable

Comparative study on individualized homoeopathic medicine using homoeopathic medical repertory as an add-on therapy versus conventional medicine in the management of essential hypertension

Not provided2 sites in 1 country60 target enrollmentStarted: October 30, 2025Last updated:

Trial Snapshot

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
60
Locations
2
Primary Endpoint
Reduction in Blood Pressure

Study Overview

Brief Summary

The present study is a comparative clinical trial designed to evaluate the effectiveness of individualized homoeopathic medicines, selected through Murphys Homoeopathic Medical Repertory, versus conventional medicine in the management of essential hypertension. Hypertension is a significant global health burden, yet standardized guidelines for its homoeopathic management are lacking, with previous studies showing limited methodology and insufficient focus on repertorial data and mental emotional symptoms. This experimental, two group study will include 60 patients between 18 to 65 years with essential hypertension (SBP 130 to149 mmHg, DBP 90 to 99 mmHg) and will be conducted over 18 months at Dr. D.Y. Patil Homoeopathic Medical College, Pune. One group will receive individualized homoeopathic medicines with conventional medicine while the other will receive conventional treatment with placebo, with outcomes assessed through regular blood pressure monitoring and statistical analysis. The study aims to determine whether individualized homoeopathy can provide an effective, holistic, and safe alternative or complement to conventional antihypertensive therapy.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Participant Blinded

Eligibility Criteria

Ages
18.00 Year(s) to 65.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Patient suffering from the essential hypertension [SBP: 130-149 mmHg and DBP 90-99 mmHg].
  • Participants who fulfilling the diagnostic criteria for essential hypertension as defined by the 2017 guidelines.
  • Patient who is willing to give informed consent.

Exclusion Criteria

  • The cases of secondary hypertension [ SBP more than 140 mmHg and DBP more than 100 mmHg].
  • Individual having chronic renal disease.

Outcomes

Primary Outcomes

Reduction in Blood Pressure

Time Frame: Reduction in Blood Pressure | Change in systolic blood pressure (SBP) and diastolic blood pressure (DBP) from baseline to the end of study period (measured monthly) Comparing the effects of individualized homoeopathic medicine with conventional treatment in the management of essential hypertension. | 1 month

Change in systolic blood pressure (SBP) and diastolic blood pressure (DBP) from baseline to the end of study period (measured monthly) Comparing the effects of individualized homoeopathic medicine with conventional treatment in the management of essential hypertension.

Time Frame: Reduction in Blood Pressure | Change in systolic blood pressure (SBP) and diastolic blood pressure (DBP) from baseline to the end of study period (measured monthly) Comparing the effects of individualized homoeopathic medicine with conventional treatment in the management of essential hypertension. | 1 month

Secondary Outcomes

  • Repertorial analysis outcomes observation of frequently indicated rubrics and remedies in essential hypertension cases.(Need for additional or concomitant medication)

Investigators

Sponsor
Not provided
Responsible Party
Principal Investigator
Principal Investigator

DR Anveksha Tukaram Thombare

Dr D Y Patil Homoeopathic Medical College and Research Centre

Study Sites (2)

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