Comparative study on individualized homoeopathic medicine using homoeopathic medical repertory as an add-on therapy versus conventional medicine in the management of essential hypertension
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Enrollment
- 60
- Locations
- 2
- Primary Endpoint
- Reduction in Blood Pressure
Study Overview
Brief Summary
The present study is a comparative clinical trial designed to evaluate the effectiveness of individualized homoeopathic medicines, selected through Murphys Homoeopathic Medical Repertory, versus conventional medicine in the management of essential hypertension. Hypertension is a significant global health burden, yet standardized guidelines for its homoeopathic management are lacking, with previous studies showing limited methodology and insufficient focus on repertorial data and mental emotional symptoms. This experimental, two group study will include 60 patients between 18 to 65 years with essential hypertension (SBP 130 to149 mmHg, DBP 90 to 99 mmHg) and will be conducted over 18 months at Dr. D.Y. Patil Homoeopathic Medical College, Pune. One group will receive individualized homoeopathic medicines with conventional medicine while the other will receive conventional treatment with placebo, with outcomes assessed through regular blood pressure monitoring and statistical analysis. The study aims to determine whether individualized homoeopathy can provide an effective, holistic, and safe alternative or complement to conventional antihypertensive therapy.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patient suffering from the essential hypertension [SBP: 130-149 mmHg and DBP 90-99 mmHg].
- •Participants who fulfilling the diagnostic criteria for essential hypertension as defined by the 2017 guidelines.
- •Patient who is willing to give informed consent.
Exclusion Criteria
- •The cases of secondary hypertension [ SBP more than 140 mmHg and DBP more than 100 mmHg].
- •Individual having chronic renal disease.
Outcomes
Primary Outcomes
Reduction in Blood Pressure
Time Frame: Reduction in Blood Pressure | Change in systolic blood pressure (SBP) and diastolic blood pressure (DBP) from baseline to the end of study period (measured monthly) Comparing the effects of individualized homoeopathic medicine with conventional treatment in the management of essential hypertension. | 1 month
Change in systolic blood pressure (SBP) and diastolic blood pressure (DBP) from baseline to the end of study period (measured monthly) Comparing the effects of individualized homoeopathic medicine with conventional treatment in the management of essential hypertension.
Time Frame: Reduction in Blood Pressure | Change in systolic blood pressure (SBP) and diastolic blood pressure (DBP) from baseline to the end of study period (measured monthly) Comparing the effects of individualized homoeopathic medicine with conventional treatment in the management of essential hypertension. | 1 month
Secondary Outcomes
- Repertorial analysis outcomes observation of frequently indicated rubrics and remedies in essential hypertension cases.(Need for additional or concomitant medication)
Investigators
DR Anveksha Tukaram Thombare
Dr D Y Patil Homoeopathic Medical College and Research Centre