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The effect of melatonin, clonidine, and gabapentin on reducing the preoperative anxiety and postoperative pain in patients undergoing laparoscopic cholecystectomy

Phase 3
Conditions
Anxiety NOS
Condition 1: Epigastric Pain. Condition 2: Anxiety.
Pain localized to upper abdomen
Registration Number
IRCT2014041217231N1
Lead Sponsor
Tehran University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
88
Inclusion Criteria

Inclusion Criteria:
Patients scheduled for elective laparoscopy cholecystectomy; Signing the informed written consent;

Exclusion Criteria

History of congenital heart diseases; History of heart valve diseases; History of liver or kidney diseases; History of psychological disorders; Opioid addiction; Uncontrolled hypertension; Patients with verbal or communication difficulties

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Anxiety. Timepoint: The night before the surgery and when entering the operating room. Method of measurement: STAI questionnaire.;Pain. Timepoint: 2 h before and 1 h, 2 h, 6 h, 12 h, and 24 h after the surgery. Method of measurement: VAS, PCA.
Secondary Outcome Measures
NameTimeMethod
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