Evaluation Of Cognitive Functions In Adult Individuals With COVID-19
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Montreal Cognitive Assessment Test (MoCA)
研究概览
简要总结
This study was aimed to evaluate the post-infection cognitive functions of adult individuals with COVID-19. 50 individuals with COVID-19 and 50 healthy control groups were included in the study. Cognitive functions of individuals with COVID19 compared with healthy individuals.
详细描述
This study was aimed to evaluate the post-infection cognitive functions of adult individuals with COVID-19. Fifty COVID-19 patients, aged between 18-50 years, who had positive RT-PCR test in the last 60 days and later recovered, were included in the study. The study group was compared with the control group consisting of 50 healthy individuals in whom gender, age and education year has not difference significantly. Participants' global cognitive skills were measured by the Montreal Cognitive Assessment Test (MoCA), the Clock Drawing Test and memory functions, the Öktem Verbal Memory Processes Test (Ö-SBST), the attention functions by the Digit Span Forward and Digit Span Backwards Test, the executive functions by Categorical Fluency, Phonemic Fluency, the Stroop Test, Trail Making Test A and B, visuospatial skills were evaluated with the Rey-Osterrieth Complex Figure Test (ROCF), and behavioral symptoms were evaluated with the Neuropsychiatric Inventory (NPI). The study group was evaluated between 21 and 60 days from the onset of the disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Having positive for the COVID-19 RT-PCR test and turned negative in the last 60 days.
- •be 18-50 years old
- •21 days have passed since the onset of the disease
排除标准
- •Having any neurological or psychiatric illness
结局指标
主要结局
Montreal Cognitive Assessment Test (MoCA)
时间窗: Any day between 21-60 days from the date of COVID-10 RT-PCR test positive.
It is a test that measures attention and concentration, executive functions, memory, language, visuospatial skills, abstract thinking, calculation and orientation skills in order to distinguish individuals with mild cognitive impairment from healthy individuals.
次要结局
- Clock Drawing Test(Any day between 21-60 days from the date of COVID-10 RT-PCR test positive.)
- Öktem Verbal Memory Processes Test (Ö-SBST)(Any day between 21-60 days from the date of COVID-10 RT-PCR test positive.)
- Digit Span(Any day between 21-60 days from the date of COVID-10 RT-PCR test positive.)
- Verbal Fluency Test(Any day between 21-60 days from the date of COVID-10 RT-PCR test positive.)
- Stroop Test(Any day between 21-60 days from the date of COVID-10 RT-PCR test positive.)
- Trail Making Test(Any day between 21-60 days from the date of COVID-10 RT-PCR test positive.)
- Rey-Osterrieth Complex Figure Test (ROCF)(Any day between 21-60 days from the date of COVID-10 RT-PCR test positive.)
- Neuropsychiatric Inventory (NPI)(Any day between 21-60 days from the date of COVID-10 RT-PCR test positive.)
研究者
Büşra Tüfekçi
Principal Investigator
Medipol University