Intubation Prediction in COVID-19 Patients Treated With Awake Prone Positioning

Completed

• Conditions: Acute Hypoxemic Respiratory Failure; SARS-CoV-2 Virus

• Registration Number: NCT05060926
• Lead Sponsor: University of Lausanne Hospitals

Brief Summary

Retrospective study in Sars-Cov 2 patients hospitalised in ICU. We aim to explore the effects of Awake prone positioning on oxygenation and intubation rate.

Detailed Description

Not available

Study Timeline

• Status Verified: 2021-09
• Study Start: 2021-09-16
• Study First Submitted: 2021-09-16
• Study First Submitted QC: 2021-09-27
• Study First Posted: 2021-09-29
• Primary Completion: 2022-04-30
• Study Completion: 2022-04-30
• Last Update Submitted: 2022-06-02
• Last Update Posted: 2022-06-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 42

Inclusion Criteria

• Sars-CoV-2 pneumonia
• ICU stay
• Severe hypoxemia but non intubated

Exclusion Criteria

• Intubated before admission
• Denied consent for data analysis
• Do not intubate order at ICU admission

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intubation rate	Once between ICU admission and extubation

Secondary Outcome Measures

Name	Time	Method
Respiratory pattern	Within 6 hours before and 6 hours after each pronation
Alveolo-arterial gradient change	Within 6 hours before and 6 hours after each pronation
Blood gas analysis	Within 6 hours before and 6 hours after each pronation
Mortality	Up to 28 days from ICU admission

Trial Locations

Locations (1)

Lausanne University Hospitals; 🇨🇭 Lausanne, Vaud, Switzerland