MedPath

eural representations of food stimuli in Anorexia Nervosa

Completed
Conditions
Anorexia nervosa
eating disorder
10014067
Registration Number
NL-OMON52810
Lead Sponsor
niversiteit Maastricht
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
45
Inclusion Criteria

In order to be eligible to participate in this study, a subject must meet all
of the following criteria:
Anorexia Nervosa:
1. Female
2. Have a current diagnosis of Anorexia Nervosa (restrictive subtype)
3. Be a patient at MUMC (or other participating medical centres)
4. Have a BMI between 13 and 18
5. Be able to give informed consent
6. Must be >= 16 years of age
5.7. Able to speak and read Dutch
6.8. Not allergic or intolerant to the liquid stimulidairy drinks

Healthy Control:
1. Female
2. Not have a current or previous (within the past five years) diagnosis of an
eating disorder, anxiety, depression and or OCD.
3. Have a healthy BMI (18.5 - 25).
4. Be able to give informed consent.
4.5. Must be >= 16 years of age
5.6. Able to speak and read Dutch.
6.7. Not allergic or intolerant to the liquid stimuli

Exclusion Criteria

For all participants:.
1. Allergies or Intolerances to ingredients contained in the liquid stimuli
2. Left-handedness
3. Existing medically diagnosed neurological disorders
4. Standard fMRI exclusion criteria (e.g., metallic medical devices or
implants, pregnancy, piercings that cannot be removed). See E2 appendix C of
the submitted file.

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Study 1: The effect of these manipulated attentional focus on brain regions<br /><br>related to inhibitory control and reward processing.<br /><br>Study 2: The effect of informed and uninformed food caloric content on neural<br /><br>expectancy response and initial neural taste response. </p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Study 2: The effect of palatability vs tension on neural activity while tasting<br /><br>food. </p><br>
© Copyright 2025. All Rights Reserved by MedPath