临床试验/NCT07724379

NCT07724379已完成不适用

A Prospective Study of Tetanus Antibody Protective Efficacy in Healthy Populations in Beijing

Peking University First Hospital1 个研究点分布在 1 个国家目标入组 2,009 人开始时间: 2025年5月4日最近更新: 2026年7月24日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Peking University First Hospital
入组人数: 2,009
试验地点: 1
主要终点: Tetanus Antibody Level

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The goal of this observational study is to learn about antibody level of tetanus of adults in high-income city of china. The main question it aims to answer is:

Analysis of tetanus antibody distribution across different age groups
Evaluation of the TQS method for determining antibody status
Correlation between primary vaccination history and tetanus antibody concentrations Blood samples were voluntarily provided by adult healthy participants for tetanus antibody analysis over a continuous collection period of more than one year.

研究设计

研究类型: Observational
观察模型: Other
时间视角: Prospective

入排标准

年龄范围: 18 Years 至 —（Adult, Older Adult）
性别: All
接受健康志愿者: 是

入选标准

•Voluntarily sign the informed consent form；
•Be aged 18 years or older；
•Be willing to provide a blood sample for biochemical testing

排除标准

•Receipt of immunoglobulin, blood, or blood products within 6 months prior to enrollment；
•Refusal to provide tetanus vaccination history (including vaccination records, CDC vaccine administration registry, or subject's recall)；
•Individuals with recent tetanus vaccination (within 5 years), acute illness, pregnancy, or immunosuppressive conditions will be excluded

结局指标

主要结局

Tetanus Antibody Level

时间窗: Baseline (single blood draw at enrollment)

Single blood draw

次要结局

tetanus antibody level by TQS/mTQS method(Baseline (single blood draw at enrollment))

研究者

发起方

Peking University First Hospital

申办方类型

Other

责任方

Principal Investigator

主要研究者

Liu Si

Chief Physician， Department Director

Peking University First Hospital

研究点 (1)

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