Total arterial grafting versus internal mammary and saphenous vein grafting for coronary artery bypass graft surgery

Completed

• Conditions: Ischaemic heart disease; Circulatory System; Chronic ischaemic heart disease

• Registration Number: ISRCTN80270323
• Lead Sponsor: Capital Health Authority, New Halifax Infirmary (Canada)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-12-08
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1. Consecutive patients between the ages of 60 and 75 years of age*, either sex
2. Undergoing non-emergent isolated CABG surgery for 3 vessel coronary disease
3. Have not already been enrolled in another study

*The average age of patients undergoing CABG surgery at the QEII is approximately 70 with 50% of patients between the age restrictions. The age limit of 75 is an attempt at increasing long-term follow-up of patients which would be limited in octogenarians.

Exclusion Criteria

1. Scheduled to undergo emergency or emergency salvage surgery
2. Angiographically ungraftable coronary territories
3. Prior surgical coronary revascularisation
4. Evidence of varicose veins on pre-operative physical examination which would preclude the use of the greater saphenous vein as a graft conduit
5. Previous radiation treatment to their chest area (which would make the utility of internal mammary arteries questionable)
6. Relative contraindications to computed tomography (CT) angiography such as pregnancy, chronic renal insufficiency (creatinine greater than 120 umol/L), or allergy to contrast media

Study & Design

• Study Type: Interventional
• Study Design: Not specified