Comparison of the effect of Budesonide nasal spray, Betamethasone nasal drop, and Budesonide nebulizing suspension on sinonasal polyposis recurrence

Phase 3

Recruiting

• Conditions: Nasal polyp, unspecified; Sinonazal polyposis.; J33.9

• Registration Number: IRCT20201021049095N1
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 1 November 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 108

Inclusion Criteria

FESS candidates with sinonasal polyposis
patients between 18 to 70 years old

Exclusion Criteria

Absence of underlying diseases, including CF, Wegener's, Kartagener, sarcoidosis, vasculitis, or rheumatic diseases;
Receiving no systemic corticosteroids for up to 4 weeks before surgery;
ages below 18 or higher than 70 years olds

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Recurrence. Timepoint: 1 and 6 months after surgery. Method of measurement: Diagnostic endoscopy.;Degree of recurrence. Timepoint: 1 and 6 month after surgery. Method of measurement: Modified L K –SCALE endoscopy.;Visual Analog Scale (VAS) for scoring the symptoms of sinusitis and polyps. Timepoint: 1 and 6 months post operation. Method of measurement: questioning from patients.;Self rated satisfaction of surgery outcomes. Timepoint: 1 and 6 months post surgery. Method of measurement: questioning from patients.;Need to revision. Timepoint: 1 and 6 months post surgery. Method of measurement: examination and questioning from patients.

Secondary Outcome Measures

Name	Time	Method
Side effects including dryness and Epistaxis. Timepoint: 1 and 6 months after surgery. Method of measurement: clinical examination.