THE EFFECT OF ARGININE AND GLUTAMINE ON COVID-19 PATIENTS OUTCOME: A RANDOMIZED CLINICAL TRIAL
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- ICU Admission
研究概览
简要总结
The goal of this clinical trial is to determine effect of arginine and glutamine on outcome of COVID-19 patients. The main questions it aims to answer are:
-to test the effect of oral nutritional supplements containing arginine and glutamine on covid-19 patients outcome Dr. M. Djamil General Hospital Padang
Participants will given ONS containing arginine and glutamine. Researchers will compare intervention group with control group to see if ONS affected outcome of COVID-19 patients
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients confirmed positive for COVID-19
- •Age over 17 years
- •The patient can take food orally
排除标准
- •Patients with restricted fluid intake
- •Patients who cannot take food orally
- •suffering from diabetes mellitus and kidney failure
研究组 & 干预措施
intervention group
The intervention group was given a High-Calorie High-Protein + ONS diet containing 4.8 g arginine and 2 g glutamine, namely Neomune 2x 200 cc, purchased from Otsuka Pharmaceutical Co., Ltd
干预措施: Neomune (Dietary Supplement)
control group
the control was administered with a High-Calorie High-Protein diet + ONS hospital standard.
干预措施: Neomune (Dietary Supplement)
结局指标
主要结局
ICU Admission
时间窗: 3 months
A patient is likely to be admitted to ICU during intervention period
length of stay
时间窗: 3 months
length of stay of patients in hospital
Outcome
时间窗: 3 months
Outcome Measures of patients (discharge or dead)
次要结局
- Il-6 and CRP Levels(3 months)
研究者
Sari Bema Ramdika
Ms
Universitas Sriwijaya