Antenatal Ultrasound Diagnosis of Periventricular Pseudocysts and Postnatal Outcome

Not Applicable

Completed

• Conditions: Periventricular Pseudocysts
• Interventions: Other: questionnaire

• Registration Number: NCT05546801
• Lead Sponsor: University Hospital, Bordeaux

Brief Summary

The present study aims to improve the information given to the parents during the screening of periventricular pseudocysts in the Pluridisciplinary Center of Prenatal Diagnosis, with retrospective cases screened during the last 5 years in university hospital of Bordeaux.

Detailed Description

Antenatal ultrasound screening for periventricular pseudocysts is steadily increasing, enabled in part by technological advances in ultrasound equipment.

Most of studies dealing with periventricular pseudocysts and subsequent neurodevelopment are based on neonatal screening, mostly performed in neonatal units.

Current data in the literature on the postnatal outcome of children screened antenatally are scarce; there are only 5 cohort studies with small numbers on the subject.

The present study aims to improve the information given to the parents during the screening of periventricular pseudocysts in the Pluridisciplinary Center of Prenatal Diagnosis, with retrospective cases screened during the last 5 years in university hospital of Bordeaux.

Study Timeline

• Study First Submitted: 2022-09-15
• Study First Submitted QC: 2022-09-15
• Study First Posted: 2022-09-21
• Study Start: 2022-10-12
• Primary Completion: 2022-12-01
• Study Completion: 2022-12-01
• Status Verified: 2023-02
• Last Update Submitted: 2023-02-21
• Last Update Posted: 2023-02-22

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

• Adult patient diagnosed with a periventricular cyst during a prenatal ultrasound at Bordeaux University Hospital between January 1, 2016 and December 31, 2020.
• Patient affiliated with or benefiting from a social security plan.
• Oral informed consent.

Exclusion Criteria

• Subarachnoid cyst
• Blake's pouch cyst
• Choroid plexus cyst
• Periventricular leukomalacia
• Poor understanding of French
• Patient under legal protection.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
questionnaire	questionnaire	Questionnaire on postnatal development

Primary Outcome Measures

Name	Time	Method
postnatal child development	Baseline	composite criterion as follows: Delayed acquisition is defined according to the standards of the Pediatric Society: age of sitting \> 8 months, age of walking \> 18 months, ability or not to associate 3 words at age 3. The use of a medical profession concerns follow-up by a speech therapist, a psychomotrician or a physiotherapist. It is not necessarily a periodic follow-up but a minimum of 2 consultations after the "assessment" consultation.; The scoring defines 2 groups,; * children with 0 points considered with a "normal" post-natal development; * children with 1 point or more considered with a post-natal development disorder.

Secondary Outcome Measures

Name	Time	Method
mother's medical history	Baseline	mother's medical history
medical history of the child	Baseline	medical history of the child

Trial Locations

Locations (1)

CHU Bordeaux; 🇫🇷 Bordeaux, France