Half-normal Saline in Atrial Fibrillation Ablation
Not Applicable
Completed
- Conditions
- Atrial Fibrillation
- Interventions
- Drug: Half-normal salineDrug: Normal saline
- Registration Number
- NCT03498586
- Lead Sponsor
- Texas Cardiac Arrhythmia Research Foundation
- Brief Summary
The study evaluates the use of half-normal saline as an irrigant for open-irrigated catheters during atrial fibrillation ablation. By increasing the efficacy of radiofrequency energy-mediated lesion formation, half-normal saline has the potential to reduce procedural times and improved acute and long-term outcomes.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 99
Inclusion Criteria
Not provided
Exclusion Criteria
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Half-normal saline Half-normal saline - Normal saline Normal saline -
- Primary Outcome Measures
Name Time Method acute pulmonary veins, and left atrial appendage (if applicable) reconnection intraprocedural total radiofrequency ablation time, and total procedure time intraprocedural freedom from atrial tachycardia/atrial fibrillation > 30 seconds without antiarrhythmic drugs 1 year
- Secondary Outcome Measures
Name Time Method freedom from atrial tachycardia/atrial fibrillation > 30 seconds with or without antiarrhythmic drugs 1 year long-term pulmonary veins, left atrial appendage (if applicable), and coronary sinus (if applicable) reconnection in case of a repeat procedure performed during the study follow-up (an average of 1 year)
Trial Locations
- Locations (2)
Texas Cardiac Arrhythmia Institute, St. David's Medical Center
🇺🇸Austin, Texas, United States
Sunnybrook Health Sciences Centre
🇨🇦Toronto, Ontario, Canada