Direct Versus US Guided PECS Block on Controlling Postmastectomy Pain

Not Applicable

Completed

• Conditions: Postmastectomy Pain
• Interventions: Drug: general anaesthetic technique only; Procedure: Direct pecs block; Procedure: Ultrasound guided pecs block

• Registration Number: NCT05825430
• Lead Sponsor: Al-Azhar University

Brief Summary

Perioperative analgesia for surgery in carcinoma breast utilizes significant quantities of opioids as compared to cosmetic breast surgeries. Regional anesthesia reduces the need for perioperative opioids and thus may improve the outcome. The investigators decided to perform the modified pectoral nerve block ( Pec II) under vision after resection of tumor, without ultrasound and compare the postoperative analgesic and opioid sparing effects of the nerve block with ultrasound guided modified pectoral nerve block (Pec) in patients undergoing modified radical mastectomy.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-04-09
• Study Start: 2023-04-15
• Study First Submitted QC: 2023-04-21
• Study First Posted: 2023-04-24
• Primary Completion: 2023-06-15
• Study Completion: 2023-06-15
• Status Verified: 2023-08
• Last Update Submitted: 2023-08-04
• Last Update Posted: 2023-08-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

• 20 - 50 years
• ASA I or II undergo elective simple mastectomy

Exclusion Criteria

• patients with diabetes mellitus i
• Intradialytic hypotension,
• chronic kidney disease and Bronchial Asthma

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control group	general anaesthetic technique only	Patients will not receive any block
Direct pecs block group	Direct pecs block	Pec I block will be given with 10 ml bupivacaine 0.25% which injected between two pectoral muscles and pecs II block will be given with 20 ml bupivacaine 0.25%.which given between pectoralis minor muscle and serratus muscle. Patients will receive direct pecs block by surgeon after closure of pectoralis muscle under direct vision and before skin closure.
Ultrasound guided pecs	Ultrasound guided pecs block	Pec I block will be given with 10 ml bupivacaine 0.25% which injected between two pectoral muscles and pecs II block will be given with 20 ml bupivacaine 0.25%.which given between pectoralis minor muscle and serratus muscle. Patients will receive ultrasound guided pecs block done after induction and before skin incision.

Primary Outcome Measures

Name	Time	Method
Total morphine consumption	24 hours postoperative	the amount of total postoperative morphine consumption

Secondary Outcome Measures

Name	Time	Method
postoperative visual analogue scale (VAS)	24 hours postoperatively	The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between 0 "no pain" and 10 "worst pain.

Trial Locations

Locations (2)

Neveen Kohaf; 🇪🇬 Tanta, Egypt

Haney Baumey; 🇪🇬 Banhā, Egypt