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Omega-3 Fatty Acids for Major Depressive Disorder During Pregnancy

Not Applicable
Completed
Conditions
Depressive Disorder
Interventions
Dietary Supplement: Omega-3 fatty acids
Registration Number
NCT00618865
Lead Sponsor
National Science Council, Taiwan
Brief Summary

Whether high-dose omega-3 fatty acids supplement would be an effective treatment in patients with major depressive disorder during pregnancy and breast-feeding.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
36
Inclusion Criteria
  • Eligible participants were pregnant women, aged 18 to 40 years, with major depressive disorder onset between their 16th week (second trimester) and 32nd week (third trimester) of gestation at the Department of Obstetrics.
Exclusion Criteria
  • Subjects were excluded with a DSM-IV diagnosis of bipolar disorders, psychotic disorders, substance abuse or dependence for at least 3 months, or any Axis-II diagnosis of borderline or antisocial personality disorder.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
1Omega-3 fatty acidsomega-3 fatty acid with 2.2 g of eicosapentanoic acid (EPA) and 1.2 g of docosahexanoic acid (DHA)
2Omega-3 fatty acidsPlacebo (olive oil ethyl esters)
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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