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Clinical Trials/NCT00549627
NCT00549627
Suspended
N/A

Evaluation of the PediGuard™ for Pedicle Screw Insertion

Shriners Hospitals for Children7 sites in 2 countries108 target enrollmentAugust 2005

Overview

Phase
N/A
Intervention
Not specified
Conditions
Posterior Spinal Fusion
Sponsor
Shriners Hospitals for Children
Enrollment
108
Locations
7
Primary Endpoint
At least 90% of screws placed with the PediGuard™ will be positioned correctly in the pedicle (defined as less than 2 mm breach by CT scan).
Status
Suspended
Last Updated
17 years ago

Overview

Brief Summary

The aim of the study is to determine the relative effectiveness of the PediGuardTM , a device manufactured by SpineVision, Inc, for placement of a pedicle screw pilot (drill) hole and for reducing pedicle screw breaches during thoracic and lumbar pedicle screw fixation of the spine.

Hypothesis #1 The PediGuardTM will be more accurate for pedicle screw placement as compared to other standard manual techniques of similar size of pedicle screw insertion. At least 90% of screws placed with the PediGuardTM will be positioned correctly in the pedicle (defined as less than 2 mm breach by CT scan). In contrast, only 80% of screws using manual placement will be positioned correctly in the pedicle.

Hypothesis #2 The PediGuardTM will not be inferior to fluoroscopic techniques for pedicle screw insertion. Both techniques will achieve at least 90% accuracy in the placement of pedicle screws.

Registry
clinicaltrials.gov
Start Date
August 2005
End Date
December 2010
Last Updated
17 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Patients undergoing primary spinal fusion with pedicle screw fixation of the spine anywhere from T1to S1
  • Subjects must be skeletally mature as defined by closed growth plates on wrist via radiographs
  • Written informed consent and assent (assent for adolescents)

Exclusion Criteria

  • Pedicle screw insertion by image guided techniques, including Fluoronav
  • Diagnoses associated with diminished bone mineral density such as osteogenesis imperfecta, severe osteopenia, neurofibromatosis
  • Severe senile osteoporosis (\> 2 standard deviations below the norm)
  • Women who are pregnant
  • Children with open growth plates
  • Previously fused spinal levels
  • Unwillingness to sign written informed consent and assent.

Outcomes

Primary Outcomes

At least 90% of screws placed with the PediGuard™ will be positioned correctly in the pedicle (defined as less than 2 mm breach by CT scan).

Time Frame: Post-op CT prior to discharge

Study Sites (7)

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