The Effect of Intradialytic Exercise on the Functional Capacity of Hemodialysis Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- Functional Capacity
研究概览
简要总结
The purpose of this study is to explore the impact of an intradialytic exercise program on functional capacity, aerobic capacity, strength, quality of life, depression, hospitalizations and intradialytic episodes of hypotension. The investigators would also like to look at the impact of exercise training over twelve weeks on hemoglobin levels as well as the clearance of potassium, phosphate and urea. Our hypothesis is that the above mentioned outcomes will positively improve over the twelve week intervention.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Cardiac and hemodynamic stability
- •Absence of severe musculoskeletal impairment
- •Increased musculoskeletal weakness
- •Vital signs within normal range for exercise
- •Desire/motivated to exercise
- •Clearance from nephrologist and Kinesiologist
排除标准
- •Compromised cardiac profiles
- •Hemodynamic instability
- •Severe bone disease
- •Medical conditions which contraindicate exercise
结局指标
主要结局
Functional Capacity
时间窗: 12 weeks
Functional capacity is measured by the DASI score which gives an estimated V02 peak in ml/min/kg. The difference between the mean score at baseline and 12 weeks will be determined.
次要结局
- Urea removal(12 weeks)
- Phosphate levels(12 weeks)
- Bioimpedance derived volume and body mass determinations(12 weeks)
- Hospitalizations(12 weeks)
- Quality of life(12 weeks)
- Hypotension(12 weeks)
- Aerobic capacity(12 weeks)
- Strength(12 weeks)
- Hemoglobin levels(12 weeks)
- Potassium levels(12 weeks)
研究者
Dr Jennifer MacRae
Principal Investigator
University of Calgary