Lung Health of Early Chronic Obstructive Pulmonary Disease: a Multi-center Cohort Study

Ting YANG2 sites in 1 country1,550 target enrollmentAugust 1, 2022

ConditionsCOPD

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: COPD
Sponsor: Ting YANG
Enrollment: 1550
Locations: 2
Primary Endpoint: Lung function decline in Pre-COPD and Mild-COPD patients
Status: Recruiting
Last Updated: last year

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This is a multi-center, prospective, cohort study in early COPD patients. This study aims to elucidate the lung function decline and its association with smoking and other risk factors. Other biomarkers and image markers from chest CT scan are also analyzed to investigate the lung function in early COPD patients.

Registry

clinicaltrials.gov

Start Date

August 1, 2022

End Date

December 31, 2027

Last Updated

last year

Study Type

Observational

Sex

All

Investigators

Sponsor

Ting YANG

Responsible Party

Sponsor Investigator

Principal Investigator

Ting YANG

Vice Director of Respiratory Center

China-Japan Friendship Hospital

Eligibility Criteria

Inclusion Criteria

•Gender: male or female
•Age: 35-75 years old
•post-bronchodilator spirometry: FEV1/FVC \< 0.8 and FEV1%pred ≥80%

Exclusion Criteria

•Other diseases may affect lung function, like lung cancer, bronchiectasis, interstitial lung disease or chest surgery.
•BMI \> 35 kg/m2
•Dementia or other severe neurological disease
•Conditions that contraindicated lung function test