Assessment of Impact of High Temperature Climate on Urinary Iodine Concentration in Women of Reproductive Age
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 363
- 试验地点
- 2
- 主要终点
- Urinary iodine concentration
研究概览
简要总结
Urinary iodine concentration (UIC) is the recommended biomarker of iodine status in populations. Yet, the influence of climate on UIC remains unclear. Hot climate may reduce urine volume and consequently increase UIC independent of iodine status. This could lead to an overestimation of population iodine intake, thus masking iodine deficiency in vulnerable groups.
In this longitudinal observational cohort study in women of reproductive age we will collect 24h and spot urine samples in the summer and winter season. The influence of high temperature climates on UIC, measured and estimated urinary iodine excretion will be estimated.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 49 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Urinary iodine concentration
时间窗: 6 months
Measured in 24h urine collections
次要结局
- Urinary iodine excretion(6 months)
研究者
Prof. Michael B. Zimmermann
Prof. Dr.
Swiss Federal Institute of Technology