Effect of ksheerabala taila capsules in knee osteoarthritis

Phase 2

Not yet recruiting

• Conditions: Health Condition 1: M170- Bilateral primary osteoarthritis of knee

• Registration Number: CTRI/2024/03/063963
• Lead Sponsor: Dr T U Aravinth

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 1 April 2024

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients with Signs and Symptoms of Sandhigata vata as per ayurvedic classics

Patients fulfilling the diagnostic criteria and diagnosed previously as per American College of Rheumatology classification criteria of OA of knee

Affected Knee joint is single or both knees

Pain in the knee joint greater than or equal to 3 months

Exclusion Criteria

Gross disability like bedridden and confined to wheelchair

Patients with Rheumatic Arthritis Gout Osteoporosis and other Musculoskeletal system disorders

Patients with other major systematic disorders which interfere with treatment will be excluded like Uncontrolled Diabetic Mellitus and Hypertension

Patients with ligamental or any other knee joint injury

Patients with history of Knee surgery

Use of NSAIDS Analgesics Intra articular steroid injections within the past period of 2 weeks

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary Assessment <br/ ><br>Interleukin 6 <br/ ><br>Pain Visual Analogue Scale <br/ ><br>Western Ontario and McMaster University Osteoarthritis Index <br/ ><br>WHO Quality Of Life BREF <br/ ><br>Ayurverdic Assessment Parameters Sandhi shoola Sandhi sotha Sandhi stabdatha Sandhi atopaTimepoint: Primary Assessment <br/ ><br>Interleukin 6 on baseline and 4th week <br/ ><br>Pain Visual Analogue Scale on baseline 2nd week and 4th week <br/ ><br>Western Ontario and McMaster University Osteoarthritis Index on baseline and 4th week <br/ ><br>WHO Quality Of Life BREF on baseline and 4th week <br/ ><br>Ayurverdic Assessment Parameters <br/ ><br>Sandhi shoola <br/ ><br>Sandhi sotha <br/ ><br>Sandhi stabdatha <br/ ><br>Sandhi atopa <br/ ><br>On baseline 2nd week and 4th week

Secondary Outcome Measures

Name	Time	Method
Goniometry of the Knee joint <br/ ><br>Walking speedTimepoint: Goniometry on 0th day and 30th day <br/ ><br>Walking speed on 0th day 15th day and 30th day