Acute Preoperative Pain and Chronic Post-surgical Pain in Emergency Surgery

Not Applicable

Not yet recruiting

• Conditions: Acute Pain; Opioid; Risk Factors; Emergency Surgery; Postoperative Pain; Chronic Postsurgical Pain

• Registration Number: NCT06555107
• Lead Sponsor: Centre Hospitalier Universitaire, Amiens

Brief Summary

Studies evaluating postoperative pain as a risk factor for CPSP are almost exclusively carried out in the context of scheduled surgery. As a result, the preoperative pain studied as a risk factor for chronicity is essentially a state of pain that has persisted for several weeks or even several months.

In emergency surgeries, patients are subject to acute preoperative pain of varying intensity and the duration of which may vary by a few days. A few studies have highlighted the intensity of acute preoperative pain as a factor favouring moderate to severe postoperative pain. At this point, no study has addressed the long-term consequences of this intense preoperative pain the emergency context.

An evaluation in the field of emergency surgery, where the preoperative pain is often intense and limited in time, would enable us to identify more precisely the impact of acute pain on the incidence of CPSP.

The investigators are hypothesising that the occurrence of CPSP at 3 months in patients undergoing emergency orthopaedic or abdominal surgery is associated with acute preoperative pain.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-08
• Study Start: 2024-08
• Study First Submitted: 2024-08-13
• Study First Submitted QC: 2024-08-13
• Last Update Submitted: 2024-08-13
• Study First Posted: 2024-08-15
• Last Update Posted: 2024-08-15
• Primary Completion: 2026-01
• Study Completion: 2026-04

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 693

Inclusion Criteria

• Age ≥18 years old.
• Emergency orthopaedic and/or abdominal surgery.
• Informed consent.
• Affiliation to a social security scheme

Exclusion Criteria

• Intraoperative complications that are life-threatening or require the surgical procedure to be discontinued.
• Post-operative intensive care unit admission.
• Ambulatory surgery.
• Endoscopic surgery.
• Repeat surgery at the same site in less that 3months.
• Pregnant or breast-feeding patients.
• Patients under guardianship or deprived of liberty.
• Patients suffering from psychiatric pathologies.
• Patients suffering from neurodegenerative pathologies.
• Patients for whom self-assessment of pain using a numerical scale (0-10) cannot be carried out (non-communicative patients, non-French-speaking patients, and so on).

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Frequency of CPSP	at 3 months

Trial Locations

Locations (1)

CHU Amiens-Picardie; 🇫🇷 Amiens, France