A study on immune cell exhaustion in patients with type 2 diabetes
Not Applicable
- Conditions
- type 2 diabetes
- Registration Number
- JPRN-UMIN000041917
- Lead Sponsor
- Department of Endocrinology and Metabolism, Dokkyo Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Not provided
Exclusion Criteria
1) patients with active chronic infectious diseases such as tuberculosis 2) patients with acute infectious diseases such as pneumonia 3) patients with history of chronic inflammatorys diseases such as rheumatoid arthritis 4) patients with history of cancer 5) immunodeficient patients such as those with AIDS 6) patients taking immunosuppressant, steroids, and anti-cancer drugs 7) pregnant, potentially pregnant or lactating women 8) patients with moderate renal dysfunction (male serum creatinin 1.3 mg/dL or higher, female 1.2 mg/dL or higher)
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the expression levels of co-inhibitors on peripheral blood T lymphocytes between type 2 diabetes and non-diabetic patients
- Secondary Outcome Measures
Name Time Method To compare the expression levels of co-inhibitors on peripheral blood T lymphocytes before and after the improvement of blood glucose level in type 2 diabetes patients