Consequences in ICU of Vaccination Status of Covid-19 Patients
- Conditions
- SARS CoV 2 Infection
- Registration Number
- NCT06191341
- Lead Sponsor
- Centre Hospitalier Régional Metz-Thionville
- Brief Summary
It is a retrospective cohort study aiming to describe the characteristics, management and prognosis of vaccinated patients hospitalized in the intensive care unit (ICU), in comparison with non-vaccinated patients.
- Detailed Description
In December 2019 started the first wave of Sars-Cov-2 virus infections in Wuhan, China : the start of a major, deadly global pandemic, which has so far caused more than 6 million deaths worldwide. In response to the scale of this pandemic, a large-scale vaccination campaign was rapidly in place, starting in December 2020. Despite this measure, admission of vaccinated patients to intensive care has been noticed. The aim of this study is to describe the characteristics, management and prognosis of vaccinated patients hospitalized in the intensive care unit (ICU), in comparison with non-vaccinated patients.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1058
- Adult patient with Sars-Cov-2 pneumonia confirmed by positive reverse transcription polymerase chain reaction (RT-PCR) assay and hospitalized in the general intensive care unit of the CHR de Metz-Thionville, between 01/03/2020 and 01/06/2022.
- missing data for primary or secondary outcomes
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method World Health Organisation (WHO) clinical progression scale at hospital discharge highest score during hospital stay
- Secondary Outcome Measures
Name Time Method Prognosis factors at hospital admission Vaccinal status, SARS-COV2 variant, age, sex, BMI, SOFA score, hypertension, diabetus mellitus, immubodepression
Mortality at D28 after hospital admission Rate
Trial Locations
- Locations (1)
CHR Metz-Thionville/Hopital Mercy
🇫🇷Metz, France