Clinical Efficacy of In-situ Thrombolysis in Case of Intraventricular Haemorraghia by Aneurysm Rupture

Phase 2

Completed

• Conditions: Aneurysm, Ruptured; Subarachnoid Hemorrhage
• Interventions: Procedure: drainage; Procedure: fibrinolysis in situ

• Registration Number: NCT00823485
• Lead Sponsor: Centre Hospitalier Universitaire de Nice

Brief Summary

The purpose of this study is to determine the impact of in situ fibrinolysis on the mortality at 30 days in case of subarachnoid hemorrhage.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-10
• Study First Submitted: 2009-01-14
• Study First Submitted QC: 2009-01-14
• Study First Posted: 2009-01-15
• Primary Completion: 2009-12
• Study Completion: 2009-12
• Status Verified: 2011-12
• Last Update Submitted: 2011-12-08
• Last Update Posted: 2011-12-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 19

Inclusion Criteria

• subarachnoid hemorrhage by aneurysm rupture
• severe intraventricular hemorraghia

Exclusion Criteria

• pregnant women
• hemostasis disturbance

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
2	drainage	drainage of hemorraghia
1	fibrinolysis in situ	Actylise

Primary Outcome Measures

Name	Time	Method
assessment of mortality	at 30 days

Secondary Outcome Measures

Name	Time	Method
assessment of morbidity	at 6 months

Trial Locations

Locations (1)

Neurosurgery department , Nice University Hospital; 🇫🇷 Nice, France