Once or twice daily dose of phenobarbital to control seizure in neonates

Phase 3

• Conditions: Convulsions of newborn.; Convulsions of newborn

• Registration Number: IRCT20090813002342N12
• Lead Sponsor: Mazandaran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 January 2021

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

Newborns with seizures that use IV phenobarbital

Exclusion Criteria

Neonates with liver or kidney failure

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Phenobarbital plasma concentration. Timepoint: Before starting the phenobarbital maintenance dose and at third day of maintenance therapy. Method of measurement: by High Performance Liquid Chromatography.

Secondary Outcome Measures

Name	Time	Method
The numbers of new seizurs. Timepoint: During the study time for 5 days. Method of measurement: The visual report of responsible doctor or nurse.