Early Amniotic Membrane Transplantation in Bacterial Keratitis
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 14
- 主要终点
- Time to scar formation
研究概览
简要总结
In this study Investigators are going to do early amniotic membrane transplantation (AMT) for bacterial keratitis.
详细描述
In this study investigators are going to do amniotic membrane transplantation (AMT), early in the first week for bacterial keratitis. Investigators are comparing this technique with no amniotic membrane transplantation (NAMT) in a clinical trial, Inform consent is going to be taken, then the enrolment population is added in the study. Investigators are going to compare the final scar size, the time to scar formation, perforation rate , early need to penetrating keratoplasty (PKP), risk of vision loss (being no light perception (NLP) between two groups.This trial has been approved by the review board in Tehran University of Medical Sciences.( 487/5671)
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Bacterial keratitis being in the first week of diagnosis medically undergoing treatment
排除标准
- •thinning limbal extension intraocular extension underlying disease Nocardia keratitis
结局指标
主要结局
Time to scar formation
时间窗: It needs at most 3 months
The time keratitis needs for scar to be formed
次要结局
未报告次要终点
研究者
mohammad soleimani
Assistant Professor
Farabi Eye Hospital