Does a drug dexmedetomidine have any effect on pressure on the brain which normally increases after introduction of gas in abdomen during laparoscopic surgery.
Not Applicable
- Registration Number
- CTRI/2016/11/007436
- Lead Sponsor
- AIIMS Patna
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
ASA grade 1 and 2 patients undergoing elective laparoscopic surgery.
Exclusion Criteria
•History of any intracranial pathology
•Patients with history of left ventricular failure, atrioventricular conduction block or any cardiac disease
•Any intraocular/ophthalmic pathology
•Patients with history of uncontrolled hypertension or diabetes.
•Patients with renal and hepatic derangements
•Patients taking clonidine, beta blocking drugs, calcium channel blockers, MAO inhibitors
•Pregnant & lactating women
•History of allergy to α2 agonist
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. to assess the change in optic nerve sheath diameter after pneumoperitoneum in the presence and absence of dexmedetomidine infusion.Timepoint: to assess the change in optic nerve sheath diameter 5 minutes after induction of anesthesia, 5 minutes after pneumoperitoneum, 5 minutes after patient position change and 5 minutes after desufflation.
- Secondary Outcome Measures
Name Time Method We wish to see if dexmedetomidine causes changes in intracranial pressure caused by change in positioning after pneumoperitoneum.Timepoint: 5 minutes after position change once pneumoperitoneum has been established.