Preemptive Analgesia in Cruciate Reconstruction
- Conditions
- Anterior Cruciate Ligament Injury
- Interventions
- Registration Number
- NCT01017380
- Lead Sponsor
- Prince of Songkla University
- Brief Summary
The aims of this study was to compare analgesic efficacy of preoperative administration of etoricoxib versus celecoxib for post-operative pain relief after arthroscopic anterior cruciate ligament reconstruction. One hundred and two patients diagnosed as anterior cruciate ligament injury will randomized into 3 groups using opaque envelope. Both patients and surgeon were blinded to the allocation. All of the patients will be operated by one orthopaedic surgeon under regional anesthesia. Each group will be given either etoricoxib 120 mg., celecoxib 400 mg., or placebo 1 hour prior to operative incision. Post-operative pain intensity, time to first dose of analgesic requirement and numbers of analgesic used for rescue pain control and adverse events will be recorded periodically to 48 hours after surgery.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 30
- patients with anterior cruciate ligament injury age 15-50 yr
- previous knee surgery
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description placebo Celecoxib identical placebo placebo etoricoxib identical placebo
- Primary Outcome Measures
Name Time Method VAS score 6,12,24,48 hour postoperative
- Secondary Outcome Measures
Name Time Method number of analgesic used 48 hour postoperative
Trial Locations
- Locations (1)
Prince of Songkla University
🇹ðŸ‡Hat Yai, Songkhla, Thailand