IRCT20230515058202N1
Completed
N/A
Evaluating the effects of cardiac rehabilitation exercises (aerobic and endurance exercises) on cardiac function, functional capacity, quality of life and mental health of patients with thalassemia major
Bandare-abbas University of Medical Sciences0 sites50 target enrollmentTBD
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Bandare-abbas University of Medical Sciences
- Enrollment
- 50
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Thalassemia major patients who undergo regular blood transfusions and receive packed cells every month.
- •Patients receiving iron chelator with regular blood transfusion such as desferal or deferiprone at the same time.
- •Left ventricular ejection fraction equal to or more than 50%
- •New York Heart Association (NYHA) functional class I, II, or III.
- •Being in the age range of 18 to 40 years
- •Having the desire and motivation to participate in the training program
Exclusion Criteria
- •Severe exercise intolerance
- •uncontrolled arrhythmia,
- •uncontrolled angina pectoris,
- •severe kidney or lung disease,
- •musculoskeletal or neuromuscular conditions that preclude exercise or exercise testing, and signs or symptoms of ischemia and abnormal hemodynamic responses during previous incremental exercise test,
- •suffering from severe mental and psychiatric diseases,
- •use of psychoactive drugs,
- •uncontrolled blood pressure and diabetes,
- •clinical evidence of other secondary causes of pulmonary hypertension including HIV infection, hepatitis virus infection, Collagen vascular diseases, cirrhosis, chronic obstructive airway diseases and acquired heart disease associated with pulmonary hypertension.
Outcomes
Primary Outcomes
Not specified
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