Association of Two Desensitizing Protocols to Control Dentinal Hypersensitivity in Non-carious Lesions

Not Applicable

Completed

• Conditions: Dental Hypersensitivity
• Interventions: Radiation: Photon Laser III-DMC (with irradiation emission) + My First- Colgate; Other: Photon Laser III-DMC (without radiation emission) + My First- Colgate; Other: Photon Laser III-DMC (without radiation emission) + Sensodyne® Rapid Relief / GSK; Combination Product: Photon Laser III-DMC (with irradiation emission) +Sensodyne® Rapid Relief / GSK

• Registration Number: NCT04642001
• Lead Sponsor: Universidade Federal do Para

Brief Summary

This randomized, double-blind clinical trial evaluated the effect of photobimodulation associated with 8% strontium acetate in the treatment of dentin hypersensitivity in non-carious lesions and analyzed the risk factors with the patient's quality of life.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-08-07
• Primary Completion: 2020-09-15
• Status Verified: 2020-11
• Study Completion: 2020-11-05
• Study First Submitted: 2020-11-11
• Study First Submitted QC: 2020-11-17
• Last Update Submitted: 2020-11-23
• Study First Posted: 2020-11-24
• Last Update Posted: 2020-11-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Age between 18 to 50 years
• Good general health
• Dental sensitivity with response ≥ 4 on the 10 cm long visual analog scale (EVA)
• Presence of at least two hypersensitive teeth with a depth of up to 1 mm (measured with a millimeter probe)
• Exposed root surface caused by abrasion, erosion or gum recession

Exclusion Criteria

• Volunteers using analgesic medication
• Presence of teeth with evidence of carious lesions, pulpitis, defective restorations and moderate or severe periodontal disease
• Patients who had undergone any whitening therapy or professional or homemade desensitizer in the last six months
• Patient with fixed orthodontic appliances
• Drug users or pregnant women were also excluded.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Group G3	Photon Laser III-DMC (with irradiation emission) + My First- Colgate	Photon Laser III-DMC (with irradiation emission) + My First- Colgate
Group G1	Photon Laser III-DMC (without radiation emission) + My First- Colgate	Photon Laser III-DMC (without radiation emission) + My First- Colgate
Group G2	Photon Laser III-DMC (without radiation emission) + Sensodyne® Rapid Relief / GSK	Photon Laser III-DMC (without radiation emission) + Sensodyne® Rápido Alívio/GSK
Group G4	Photon Laser III-DMC (with irradiation emission) +Sensodyne® Rapid Relief / GSK	Photon Laser III-DMC (with irradiation emission) + Sensodyne® Rápido Alívio/GSK

Primary Outcome Measures

Name	Time	Method
dentin sensitivity	30 days after the end of treatment	evaluation of dentinal sensitivity during treatment and one month after its end, by means of tactile and evaporative stimuli according to the visual analog scale with values from 0 to 10, with higher values indicating a worse level of pain.

Trial Locations

Locations (1)

Universidade Federal do Pará; 🇧🇷 Belém, Pará, Brazil