Ayurvedic Management of Amavata( Rheumatoid arthritis)with oral administration of shadanga guggulu along with external application of kolkulatthadi lepa.

Recruitment & Eligibility

Status: ot Yet Recruiting

Sex: Not specified

Target Recruitment: 0

Inclusion Criteria

1]Patients of either sex with age between 20 years and 60 years.

2]Patients having classical signs and symptoms (articular and extra-articular both) of Amavata mentioned in Madhava nidana along with presence of six score out of the ten score according to 2010 ACR Criteria for RA Diagnosis criteria.

3]Patients having Kapha and Vataanubandha Amavata

4]RA factor positive & negative both cases will be included.

5]Patients willing and able to participate in the study.

Exclusion Criteria

1]Patients of either sex aged below 20 years and above 60 years.

2]Patients who have developed severe crippling deformity of joints due to Rheumatoid arthritis and other disorders develop as a complication of RA.

3]Patients who are unable to walk without support and confined to wheel chair.

4]Patients having Pittanubandha Amavata. (Daha and Raga over affected joints)

5]Patients with chronicity more than 5 years.

6]Patients diagnosed with other autoimmune disorders such as SLE, multiple sclerosis, other arthritis like gouty arthritis, tuberculosis arthritis, ankylosing spondylitis.

7]Patients suffering with uncontrolled diabetes mellitus (FBS greater than 200mg/dl) and hypertension (greater than 140/90mmhg).

8]Patients receiving treatment for RA with long acting corticosteroids or DMARDs (Disease modifying antirheumatic drug) or biological agents will be excluded in the study.

9]Patients suffering from Systemic disorders like cardiac, renal, hepatic, respiratory diseases, AIDS, malignancies.

10]Pregnant and lactating women.

11]Patients who are not willing for the trial.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement in signs and symptoms of Amvata (Rheumatoid arthritis). <br/ ><br>Improvement in RAPS, DAS28 and RAQoL in patients of Amvata (Rheumatoid arthritis). <br/ ><br> <br/ ><br>Timepoint: Group-A 60days <br/ ><br>Group-B 60 days <br/ ><br> <br/ ><br>

Secondary Outcome Measures

Name	Time	Method
The trial drugs will have positive effect on quality of life of patients of Amavata (Rheumatoid arthritis) by improving the status of functional parameters (Walking time, Hand grip strength, Foot pressure) <br/ ><br>Trial drugs will be helpful in reduction in ESR, CRP and RA factor in comparison to base line. <br/ ><br>The trail drugs will reduce the frequency and intensity of exacerbation. <br/ ><br> <br/ ><br>Timepoint: Group-A 60 days <br/ ><br>Group-B 60 days