Clinical Study :The Effect of Antibacterial Nanoparticles, Incorporated in Provisional Resin Based Cement, on S.Mutans in the Margins of Provisional Restorations
试验速览
- 阶段
- 不适用
- 入组人数
- 10
- 试验地点
- 1
研究概览
简要总结
The effect of Antibacterial Nanoparticles, Incorporated in cement, on S.mutans in the margins of provisional restorations is going to be examined clinically by using two kinds of provisional cement 1. cement with out antibacterial nanoparticles.
2.cement with small addition of IABN. after one week in the mouth the crowns are to be removed and examined for the presence and quantity of s. mutans. in vitro tests of the same has shown significant reduction in bacterial population around the provisional cement as compared to the regular cement.
详细描述
Provisional cement withholding antibacterial properties may be useful in preventing caries in the margins of provisional restorations. Covalently attached antibacterial polymers are a possible solution.
The provisional restoration is important in determine the success of the therapy. The provisional restoration protects the pulp and the dentin, and is used for diagnostic purposes. Sometimes provisional restoration can stay in the oral cavity for a long period. Through this time, the abutments must get the best biological and mechanical defense. The cement should have good mechanical properties, low solubility and good adhesion. The finishing line is a place prone to caries development due to the existence of a potential gap between the provisional restoration and the tooth.
This in vivo study will evaluate the antibacterial effect of alkylated polyethylenimine nanoparticles (IPN) incorporated to temporary cement, against S.mutans. We will compare 2 temporary cement, one with, and the other without the nano particles, using the direct technique for making provisional restoration with polymethyl methacrylate.
Baldissara et.al tested 4 kinds of temporary cements in 30 acryl resin crowns, prepared on extracted teeth. They authors found that in all 4 kinds of cements there was always a micro leakage, to some degree, in the margins of the restoration. These gap and micro leakage in restorations, contribute to restoration's failure.
Composites releasing Fluoride do not have antibacterial effect after light curing. This fact can explain why plaque tends to accumulate on composites. Polymethl metacrylate resin, the material used in direct provisional crown preparation, has a low antibacterial activity.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients who need provisional restorations.
排除标准
- •Patients who got antibacterial therapy in the past 3 months.
- •Patients using chlorhexidine gluconate.
- •Pregnant women.
