ACTRN12621000557831招募中4 期
A randomised controlled trial of dexmedetomidine compared to placebo to reduce pain after spinal fusion surgery
适应症
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 128
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Adults 18 years and older having thoracic and/or lumbar spinal fusion surgery using a posterior approach.
- •Anticipated to stay at least one post-operative night in hospital.
排除标准
- •Unable or unwilling to provide consent or unable to communicate numerical rating scale pain score, including cognitively impaired, planned to remain on mechanical ventilation post-operatively or non-English speaking patients.
- •Known diagnosis of significant cardiac conduction disease (second- or third-degree heart block, sick sinus syndrome, atrial fibrillation and atrial flutter) unless a pacemaker is present.
- •Known diagnosis of severe ischemic heart disease, valvular heart disease or cardiomyopathy
- •Known diagnosis of liver cirrhosis
- •Bradycardia (heart rate (HR) < 50 bpm) in theatre suite before surgery
- •Hypotension (systolic blood pressure (SBP) < 100 mmHg) in theatre suite before surgery
- •Known diagnosis of allergy or hypersensitivity reactions to dexmedetomidine or any of the protocolised anaesthetic drugs.
- •Previously enrolled into the SPADE study.
研究者
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