A feasibility study of treatments for Dupuytren's contracture (HAND-1)

Not Applicable

Completed

• Conditions: Topic: Musculoskeletal disorders; Subtopic: Musculoskeletal (all Subtopics); Disease: Musculoskeletal; Musculoskeletal Diseases

• Registration Number: ISRCTN11164292
• Lead Sponsor: ottingham University Hospitals NHS Trust

Brief Summary

2017 protocol in: https://www.ncbi.nlm.nih.gov/pubmed/28841903 2020 results in https://www.ncbi.nlm.nih.gov/pubmed/32021696 (added 06/02/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-08-28
• Study Completion: 2017-06-30
• Last Update Posted: 24 February 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 71

Inclusion Criteria

1. Aged over 18 years.
2. One or more fingers with a Dupuytren’s contracture of >30° in the metacarpophalangeal (MCP) and/or proximal
interphalangeal joints (PIP).
3. Well defined cord(s) causing contracture.
4. No previous surgery for Dupuytren’s contracture on the same hand.
5. Willing to undergo either study procedure.
6. Able to complete follow up assessments.; Target Gender: Male & Female ; Lower Age Limit 18 years

Exclusion Criteria

1. Dupuytren's contracture of the distal interphalangeal joints (DIP) only
2. Planned dermofasciectomy or very limited fasciectomy (excision of =1cm cord segment)
3. Previously recruited into this study for treatment of either hand
4. Life expectancy less than 3 years

Study & Design

• Study Type: Interventional
• Study Design: Not specified