Adherence to Treatment with Methotrexate in Rheumatoid Arthritis: Cross-sectional study
Not Applicable
- Conditions
- Rheumatoid Arthritis
- Registration Number
- JPRN-UMIN000012680
- Lead Sponsor
- Division of Rheumatology, Department of Medicine, Showa University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 176
Inclusion Criteria
Not provided
Exclusion Criteria
1. Cognitive disorder, agitation or delirium 2. Severe psychiatric disorder 3. Patients judged inappropriate for this study by the health care provider
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method evel of adherence of methotrexate measured by the MMAS-8
- Secondary Outcome Measures
Name Time Method Relationship between the level of adherence and the clinical anchor. The clinical anchors are followed; Disease Activity Score (DAS) - 28 as the disease activity, SF-8 as QOL measurement, modified Health Assessment Questionnaire as ADL measurement, Beliefs about Medicines Questionnaire as the patients' beliefs measurement, CES-D as depression assessment, Brief Pain inventory item 2 to 5 as pain intensity assessment, and Common Terminology Criteria for Adverse Events version 4.0 as adverse events assessment. Relationship between the adherence and patients' demographics. Discriminant validity of MMAS-8 by assessing social desirability.