Randomized Study Comparing the Accuracy and Specificity of Cervical Facet Medial Branch Blocks With 0.25 ml and 0.5 ml of Local Anesthetic
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Johns Hopkins University
- Enrollment
- 20
- Locations
- 1
- Primary Endpoint
- Accuracy of injections
Study Overview
Brief Summary
Cervical facet arthropathy is a common cause of chronic neck pain. The "gold standard" for diagnosis is either blocking the facet joints, or more commonly blocking the medial branch nerves that innervate the joints. However, many studies have found a high false-positive rate when the nerves are blocked using 0.5 ml of local anesthetic. We will randomize patients to receive either cervical facet medial branch blocks with 0.25 ml of local anesthetic and contrast, or 0.5 ml. We will then do a CT scan to determine the accuracy and specificity of each block. Our hypothesis is that using the higher volume (0.5 ml) might be responsible for the high false-positive rate.
Detailed Description
Inclusion criteria: Dept. of Defense beneficiaries > 18 years of age; neck pain > 3 months duration; cervical paraspinal tenderness Exclusion criteria: Radicular signs or symptoms; use of anticoagulants or bleeding disorder.
Outcome measures: The number of blocks whereby the contrast bathes the target nerve; the number of blocks whereby the contrast spreads to the medial branch nerve at the adjacent spinal level; the number of times the contrast diffuses into the intervertebral foramen or epidural space. We will also compare pain relief over 8 hours following the block between both volumes.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age > 18 years
- •Chronic neck pain > 3 months
- •Paraspinal tenderness
Exclusion Criteria
- •Absence of radicular symptoms
- •No bleeding diathesis
- •Contrast allergy
Arms & Interventions
1
Cervical medial branch blocks with 0.25 ml of injectate
Intervention: Cervical medial branch blocks (Procedure)
2
Cervical medial branch blocks with 0.5 ml of local anesthetic and contrast
Intervention: Cervical medial branch blocks (Procedure)
Outcomes
Primary Outcomes
Accuracy of injections
Time Frame: Immediately after nerve blocks.
Secondary Outcomes
- Pain relief after nerve blocks(8 hours after blocks)
