Microwave Ablation of Resectable Liver Tumors
- Conditions
- Hepatocellular CarcinomaLiver Cancer
- Registration Number
- NCT00892255
- Lead Sponsor
- St. Joseph Hospital of Orange
- Brief Summary
The purpose of this protocol is to pathologically evaluate the destruction by microwave ablation of primary and metastatic liver tumors. The primary aim is to measure tissue destruction with the MedWaves Microwave Ablation/ Coagulation Ablation System.
- Detailed Description
Minimally invasive surgical alternatives are becoming more attractive for the treatment of malignancy.The goal is to reduce morbidity and mortality and increase the ability to treat patients in the outpatient setting. Image-guided ablation is becoming an attractive alternative because of its relative low cost, its ability to provide large regions of coagulative necrosis in a controlled fashion, and its relatively low toxicity. Although image-guided ablative techniques have been extensively investigated for the treatment of liver tumors, there has been limited experience with microwave ablation (MWA) in the liver. This study will evaluate the treatment effect of MWA in liver tumors. Patients undergoing planned surgical removal of liver tumors will have the tumors intra-operatively treated with MWA. The histological changes will be evaluated upon removal of the specimen.
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
- Diagnosis of primary or metastatic liver cancer for which surgery is planned
- All participants need to be fully able to give informed consent
- Mental or legal incompetence
- Impaired decision-making capacity
- Pregnant women may not participate
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measure of the tissue destruction with the MedWaves Microwave Ablation/ Coagulation Ablation System 30 Days Measure of the tissue destruction with the MedWaves Microwave Ablation/ Coagulation
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
The Center for Cancer Prevention & Treatment at St. Joseph Hospital
🇺🇸Orange, California, United States