Intracoronary Hypothermia as a Prevention of Reperfusion Injury in Myocardial Infarction.

Not Applicable

Recruiting

• Conditions: Myocardial Infarction; ST-Elevation Myocardial Infarction (STEMI); Reperfusion Injury; Microvascular Occlusion

• Registration Number: NCT06567249
• Lead Sponsor: Tomsk National Research Medical Center of the Russian Academy of Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-8-18
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

Inclusion Criteria:<br><br> - Acute ST-elevation myocardial infarction<br><br> - Time from onset of symptoms less than 12 hours<br><br> - Given informed consent<br><br>Exclusion Criteria:<br><br> - Contraindication to MRI<br><br> - Cardiogenic shock<br><br> - Conduction disturbance: Atrioventricular block: 2nd and 3rd degree. SA block.<br><br> - Sick sinus syndrome requiring implantable pacemaker<br><br> - Pulmonary edema<br><br> - Active inflammatory condition<br><br> - Active chemo/radiation therapy

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Infarct size (percent);Myocardial hemorrhage (percent);Microvascular obstruction (percent)

Secondary Outcome Measures

Name	Time	Method
Ejection fraction (percent);Wall motion score index (score)