Skip to main content
Clinical Trials/NCT02811029
NCT02811029
Completed
N/A

Language and Motricity in Preterm School Age Children

University Hospital, Rouen1 site in 1 country108 target enrollmentJune 29, 2016

Overview

Phase
N/A
Intervention
measurement of phonology
Conditions
Infant, Premature
Sponsor
University Hospital, Rouen
Enrollment
108
Locations
1
Primary Endpoint
Evaluation of reading speed
Status
Completed
Last Updated
2 months ago

Overview

Brief Summary

A total of 40% of neurodevelopmental difficulties have been reported in very premature infants less than 32 weeks of age. The Epipage1 study reported a decreasing prevalence of cerebral palsy (9-6%) but a high prevalence of specific cognitive neurological difficulties and an increase in school failure.

Neurocognitive difficulties are numerous: visuospatial dyspraxia, language disorders, executive function disorders as well as attention and behaviour disorders. Developmental language disorders have been rarely reported in the literature. This originally prompted our request i.e. PHRC 2010 National Multicenter: LAMOPRESCO. For the past 3 years this protocol has studied the language development of children who were born very prematurely, aged 3 and a half years free of cerebral palsy, in particular the impact of a short rehabilitation period, precise, at an early stage, and protocolized on a fundamental sensorimotor language. The principal assessment criterion was the measurement of phonology, the cornerstone of oral and written language in humans. The aim of the present project is an analysis of the effect that this specific language stimulation has on the learning of written language. The hypothesis is that a specific work modifying various aspects of a child's language, during the age of 3 to 4, alters the development of phonological skills in a sustainable way. The acquisition of reading skills is basically dependent on the quality of its phonological components. The randomized study of children up to 8 years of age in a cohort of 150 children (LAMOPRESCO) will permit to confirm or refute this hypothesis. These increasing difficulties have been reported as regards the language understanding of 3 to 15 year old children. It is as if the initial difficulties and weaknesses, which moreover constituted oral language, prevented the use or development of neural networks, which became more complex and required both an oral and written language. Are these elements which constitute phonology, at an early stage, modifiable before the close of the clinically measurable developmental window?

Registry
clinicaltrials.gov
Start Date
June 29, 2016
End Date
December 11, 2018
Last Updated
2 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
University Hospital, Rouen
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Randomization in LAMOPRESCO-1 study

Exclusion Criteria

  • None as the same population as in the LAMOPRESCO study will be included

Arms & Interventions

premature infants less than 32 weeks of age

measurement of phonology in premature infants less than 32 weeks of age who participated to LAMOPRESCO-1 study

Intervention: measurement of phonology

Outcomes

Primary Outcomes

Evaluation of reading speed

Time Frame: Day 1

Evaluation of reading speed will be assess using silent reading speed test. Patient must read a list of words during 2 minutes. The total number of read words will be analyse to calculate the reading speed.

Secondary Outcomes

  • Evaluation of syntax level(Day 1)
  • Evaluation of understanding level(Day 1)
  • Evaluation of vocabulary level, syntax and understanding(Day 1)

Study Sites (1)

Loading locations...

Similar Trials