result of vitimelin tablet and vitimelin oil in vitiligo

Phase 3

Completed

Brief Summary: Vitiligo is an acquired, chronic, pigmentary disorder characterized by the progressive loss of cutaneous melanocytes and abnormality in their normal function resulting in hypo pigmented skin area which progressively becomes amelanotic. The cause is unknown but might be involve genetic factor, autoimmunity, neurological factors, toxic metabolites and lack of melanocyte growth factor.

It can also affect the eye, the inside of mouth and hair. The condition is photosensitive. It is hard to predict whether the patches will spread and by how much. The spread might take week or the patches might remain stable for month or years.

According to Ayurveda in Charaka Samhita, Shvitra is enumerated as â€œRaktaj vicar. Bhrajak pitta which is responsible for skin colour, gets vitiatedin this disease. The combinations of Rakt and pitta dosha are mentioned asashayaashrayabhav.Shvitra is considered as aType of Kilas and Tridoshaj vyadhi. Most of Ayurveda Authors use Shvitra and Kilasa as synonyms.

Recruitment & Eligibility

Inclusion Criteria

1-Children of either gender aged group between 10.
16 years. 2- Children having classical sign and symptom and diagnosed as vitiligo / Shwitra. 3- Patient should be capable of obeying the instruction related to course of therapy.

Exclusion Criteria

1- Children below 10 years and above 16 years of age.
2- Patches more than 30% of the body, Broad continuous irregular patches.
3- Children with albinism will be excluded.
4- White anesthetic spot which are characterized of leprosy.
5- Patches in genital area and only lip area are excluded from the study.
6- Patient not fulfilling the inclusion criteria.
7- Patient suffering from any other known systemic and chronic disease / Autoimmune disorder.
8- Patient not willing to give consent for participation in the Research study.

Primary Outcome Measures

Name	Time	Method
Changes in VASI score.	3 month

Secondary Outcome Measures

Name	Time	Method
To evaluate the safety of trial drug (Vitimelin Tablet and Vitimelin Oil).	3 months

Locations (1): National Institute of Ayurveda, Jaipur
🇮🇳
Jaipur, RAJASTHAN, India
National Institute of Ayurveda, Jaipur
🇮🇳Jaipur, RAJASTHAN, India
Dr Gopal Krishan Dhakar
Principal investigator
8989844044
krishna.gopi132@gmail.com