Does a whole-food, vegan diet provide the body with a sufficient supply of vitamin B12 and vitamin D?A follow-up study
Not Applicable
- Conditions
- D51.3Other dietary vitamin B<Term class=subscript>12</Term> deficiency anaemia
- Registration Number
- DRKS00004994
- Lead Sponsor
- Gesundheitspraxis Dickendorf
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Minimum age: 16 years, both sexes, all nationalities
-Participants must be of legal age or must present a written agreement of their custodian
-Participants must be in good health
-Participants must not suffer from a lack of vitamin B12 or vitamin D as a result of a disease
-Participants must have followed their present diet (vegetarian or vegan) for at least two years
Exclusion Criteria
-Persons who suffer from a lack of vitamin B12 or vitamin D as a result of a disease
-Persons whose ability to reason could be doubted
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome:<br>Serum level of: Total B12, bioactive B12, holotranscobalamin, homocysteine, methylmalonic acid, mean cellular volume, vitamin D2 and D3<br><br>Time of investigation:<br>5 investigations in 8 months (every second month) from october 2011 to june 2012<br><br>Method:<br>Laboratory tests:<br>Total B12: CLIA<br>Holotranscobalamin: CMIA<br>Bioactive B12: direct MTP essay<br>Homocysteine: HPLC<br>Methylmalonic acid: LC-MS/MS<br>Vitamin D2 and D3: HPLC and LC-MS/MS
- Secondary Outcome Measures
Name Time Method Secondary outcome:<br>Bioactive B12: correlation coeffizient in connection with: Total-B12, Holotranscobalamin, Methylmalonic acid<br>Statitstics will be done after the end of patent investigations (6/2012);<br>Statistics will be done with Excel and SPSS