Comparison of treatment of platelet-rich plasma non-healing wounds in patients with venous abnormalities
- Conditions
- Venous insufficiencychronic ulcersC14.907.952C23.550.891
- Registration Number
- RBR-7zhgb3
- Lead Sponsor
- niversidade Estadual de Campinas
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Data analysis completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Diagnosis of chronic venous insufficiency; at most 80 years old and minimum of 18 years; ulcer with diameter 10 to 40 cm²
Exclusion criteria will be: base diseases of influence on healing, patients with malignant neoplasia in the last five years, lupus, carriers of ulcers neuropathic or arterial diseases, or any other type of ulcer in the lower limbs that is not related to chronic venous insufficiency; the patients who presented 3 (three) consecutive absences or 6 (six) alternate and the non-consent to participate in the research willingly and spontaneously, Uncontrolled Systemic Arterial Hypertension (SAH), Acquired Immunodeficiency Syndrome (HIV), Anemia, Stroke or Acute Myocardial Infarction (AMI) in the last 3 months, Renal insufficiency (creatinine more than 2 mg / dl), Liver Disease (TGO more than 2x upper limit, INR more than 1.5), surgery or major trauma in the last 2 months, pregnant woman, mental retardation, inclusion in other studies in the last 30 days and relative of first or second degree of another patient in the study group
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Healing of chronic ulcers or reduction in size or quantity of wounds, verified by macroscopic evaluation of area measurement and photography
- Secondary Outcome Measures
Name Time Method Better quality of life and decreased pain for all patients assessed by venous disease-specific quality of life questionnaire