Alveolar Ridge Preservation Using Amniotic Chorion Membrane

Not Applicable

Completed

• Conditions: Alveolar Ridge Preservation
• Interventions: Other: Amniotic Chorion Membrane only; Other: Amniotic Chorion Membrane and Bio-Oss xenograft

• Registration Number: NCT04824235
• Lead Sponsor: Hams Hamed Abdelrahman

Brief Summary

the present study is to compare the amniotic chorion membrane (ACM) alone versus the amniotic chorion membrane combined with xenograft for their efficacy in alveolar ridge preservation procedures regarding volumetric changes assessed by cone beam computed tomography (CBCT).

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-01
• Study First Submitted: 2021-03-20
• Study First Submitted QC: 2021-03-27
• Study First Posted: 2021-04-01
• Primary Completion: 2022-03-01
• Study Completion: 2024-06-01
• Status Verified: 2025-01
• Last Update Submitted: 2025-01-04
• Last Update Posted: 2025-01-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Patients require extraction of a non-restorable (premolar or anterior tooth) located in the maxillary arch and needs implant restoration.
• Type two sockets will be selected as revealed by Cone beam computed tomography(CBCT)
• Absence of any systemic disease or drugs that contraindicate oral surgery using Modified Cornell Medical Index
• Male and female within age range of 20-45 years.

Exclusion Criteria

• Smokers.
• Patients with poor oral hygiene or non-compliant patients who are not willing to perform oral hygiene measures.
• Pregnant and breast-feeding females.
• Patients with acute peri-apical infection or sinus tract.
• Vulnerable group of patients as handicapped patients, orphans,prisoners,etc

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Amnoitic Chorion Membrane only	Amniotic Chorion Membrane only	extraction sockets where ridge preservation will be performed using Chorion Membrane Alone
Amnoitic Chorion Membrane and xenograft	Amniotic Chorion Membrane and Bio-Oss xenograft	extraction sockets where ridge preservation will be performed using Chorion Membrane with Xenograft

Primary Outcome Measures

Name	Time	Method
Change in Bucco-lingual bone width	at baseline, 1 months and 4 months	Bone width will be measured using bone caliper and radiographically
Change in Corono-apical bone height	at baseline, 1 months and 4 months	Bone height using a pre-fabricated stent.
total bone volume change	at baseline, and 4 months	It will be evaluated by the use of 3D scans of patient dental models

Trial Locations

Locations (1)

Ain Shams Faculty of Dentistry; 🇪🇬 Cairo, Egypt