Alveolar Ridge Preservation Using Amniotic Chorion Membrane Alone or Combined With Xenograft (A Randomized Controlled Clinical Trial With Histological Evaluation)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Change in Bucco-lingual bone width
研究概览
简要总结
the present study is to compare the amniotic chorion membrane (ACM) alone versus the amniotic chorion membrane combined with xenograft for their efficacy in alveolar ridge preservation procedures regarding volumetric changes assessed by cone beam computed tomography (CBCT).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients require extraction of a non-restorable (premolar or anterior tooth) located in the maxillary arch and needs implant restoration.
- •Type two sockets will be selected as revealed by Cone beam computed tomography(CBCT)
- •Absence of any systemic disease or drugs that contraindicate oral surgery using Modified Cornell Medical Index
- •Male and female within age range of 20-45 years.
排除标准
- •Patients with poor oral hygiene or non-compliant patients who are not willing to perform oral hygiene measures.
- •Pregnant and breast-feeding females.
- •Patients with acute peri-apical infection or sinus tract.
- •Vulnerable group of patients as handicapped patients, orphans,prisoners,etc
研究组 & 干预措施
Amnoitic Chorion Membrane and xenograft
extraction sockets where ridge preservation will be performed using Chorion Membrane with Xenograft
干预措施: Amniotic Chorion Membrane and Bio-Oss xenograft (Other)
Amnoitic Chorion Membrane only
extraction sockets where ridge preservation will be performed using Chorion Membrane Alone
干预措施: Amniotic Chorion Membrane only (Other)
结局指标
主要结局
Change in Bucco-lingual bone width
时间窗: at baseline, 1 months and 4 months
Bone width will be measured using bone caliper and radiographically
total bone volume change
时间窗: at baseline, and 4 months
It will be evaluated by the use of 3D scans of patient dental models
Change in Corono-apical bone height
时间窗: at baseline, 1 months and 4 months
Bone height using a pre-fabricated stent.
次要结局
未报告次要终点
研究者
Hams Hamed Abdelrahman
Assistant lecturer of DPH and Clinical statistician
Alexandria University